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R Nicoletti Selected Research

3-O-methylfunicone

10/20113-O-methylfunicone, from Penicillium pinophilum, is a selective inhibitor of breast cancer stem cells.
4/20103-O-Methylfunicone, a metabolite produced by Penicillium pinophilum, modulates ERK1/2 activity, affecting cell motility of human mesothelioma cells.
8/20093-O-methylfunicone, a metabolite of Penicillium pinophilum, inhibits proliferation of human melanoma cells by causing G(2) + M arrest and inducing apoptosis.

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R Nicoletti Research Topics

Disease

8Adenocarcinoma
11/2017 - 05/2001
5Neoplasms (Cancer)
10/2017 - 12/2004
3Pancreatic Neoplasms (Pancreatic Cancer)
04/2008 - 01/2004
2Neutropenia
02/2007 - 01/2004
1Colorectal Neoplasms (Colorectal Cancer)
10/2017
1Endometrial Neoplasms (Endometrial Cancer)
10/2014
1Ovarian Epithelial Carcinoma
01/2014
1Ovarian Neoplasms (Ovarian Cancer)
01/2014
1Breast Neoplasms (Breast Cancer)
10/2011
1Mesothelioma
04/2010
1Malignant Mesothelioma
04/2010
1Melanoma (Melanoma, Malignant)
08/2009
1Neoplasm Metastasis (Metastasis)
08/2009
1Vomiting
01/2004
1Diarrhea
01/2004
1Nausea
01/2004
1Thrombocytopenia (Thrombopenia)
01/2004
1Febrile Neutropenia
01/2004
1Epiretinal Membrane (Epiretinal Membranes)
06/2003
1Proliferative Vitreoretinopathy
06/2003
1Retinal Detachment (Retinal Detachments)
06/2003
1Retinal Diseases
06/2003
1Pain (Aches)
05/2001
1Abdominal Aortic Aneurysm
01/2000
1False Aneurysm (Pseudoaneurysm)
01/2000
1Aortic Aneurysm (Aneurysm, Aortic)
01/2000

Drug/Important Bio-Agent (IBA)

8GemcitabineFDA Link
11/2017 - 05/2001
5Fluorouracil (Carac)FDA LinkGeneric
11/2009 - 05/2001
5Epirubicin (Ellence)FDA LinkGeneric
11/2009 - 05/2001
5Cisplatin (Platino)FDA LinkGeneric
11/2009 - 05/2001
33-O-methylfuniconeIBA
10/2011 - 08/2009
2Docetaxel (Taxotere)FDA Link
11/2009 - 01/2004
1AcidsIBA
10/2017
1AfatinibIBA
10/2014
1Choline (Choline Chloride)IBA
01/2014
11,3,4,5,6-pentachlorocyclohexene-1-oxideIBA
01/2014
1Choline KinaseIBA
01/2014
1Phosphorylcholine (Phosphocholine)IBA
01/2014
1Proteins (Proteins, Gene)FDA Link
04/2010
1integrin alphaVbeta5IBA
04/2010
1Messenger RNA (mRNA)IBA
04/2010
1Capecitabine (Xeloda)FDA Link
11/2009
1raltitrexed (D 1694)IBA
03/2006
1Oxaliplatin (Eloxatin)FDA LinkGeneric
03/2006
1Irinotecan (Camptosar)FDA LinkGeneric
01/2004
1Mitomycin (Mitomycin-C)FDA LinkGeneric
01/2004
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2003
1Analgesics (Analgesic Drugs)IBA
05/2001
1X 50IBA
01/2000

Therapy/Procedure

8Drug Therapy (Chemotherapy)
11/2017 - 05/2001
2Radiotherapy
10/2011 - 11/2009
2Therapeutics
04/2010 - 04/2008
2Salvage Therapy
04/2008 - 03/2006
1Combination Drug Therapy (Combination Chemotherapy)
11/2009
1Endovascular Procedures
01/2000